Perhaps you'd like to explain why the general productiveness of multiple thumb buttons and not moving the appendage half an inch to press them isn't permitted outside of the purposes of playing a game against a sufficiently large number of people.
It's not worth £135 if I can't tilt.
1. Left
2. Middle
3. Right
4. Back
5. Forward
6. DPI
7. Alt-Tab
8. Play/Pause
9. Skip Track
10. Stop after Current Track
11. Vol Up
12. Vol Down
With a tilt wheel freeing up 4/5 it's possible to make otherwise awkward multi-key shortcuts a single press - particularly ones that would otherwise require taking a hand off the mouse then putting it back afterwards to complete, and that's without even getting into macros...